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Your Gut: A Surprising Ally Against "Forever Chemicals"?
Will Loiseau
7/14/20251 min read


We hear a lot about PFAS (per- and polyfluoroalkyl substances) - those "forever chemicals" found in everything from our cookware to waterproof gear, and now, nearly omnipresent in our bodies. They're linked to some serious chronic diseases. But new research is revealing a potential defender right inside us: our gut microbiome.
A recent study reveals human gut bacteria can actually bioaccumulate PFAS.
Here's why it matters for your healthspan:
Our bodies have internal defense systems. Researchers found that various human gut bacterial strains can absorb and excrete PFAS. This suggests our internal ecosystem might play a crucial role in managing these pollutants.
The bacteria we co-exist with are storage units? When exposed to common PFAS types, strains like Bacteroides uniformis were observed to store these chemicals inside their cells, even at high concentrations, without apparent harm to the bacteria themselves. This hints at a potential way our bodies might sequester these toxins. (Sequestration is the process of isolating, removing, or binding harmful substances to prevent them from causing damage.)
We can flush out toxins. In lab experiments using mice with humanized gut microbiomes, PFAS levels in their feces were significantly higher compared to germ-free mice. This indicates that our gut microbes could be key players in flushing these persistent chemicals from the body.
This research suggests that our gut microbes don't just influence digestion and immunity - they may offer an internal line of defense against chemical exposure, helping to eliminate PFAS from our systems.
While more research is needed, these findings underscore another incredible function of our gut microbiome. It's a powerful reminder that nourishing our gut isn't just about digestion; it's about supporting a complex inner world that might be protecting us in ways we're just beginning to understand.
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